Twisted Matrix seems kinda cool.

You need:

www.python.org - Python 2.4.1, please.
www.twistedmatrix.com - I used 2.0.1 on Win32.
http://www.jezuk.co.uk/cgi-bin/view/eliza - a random Eliza script I found on the Internet.

The script (check out the coolness):

http://yoni.valhallalegends.com/stuff/elizabot.py

She is currently running on ICQ# 328085940. Enjoy :)

Twisted Matrix owns. I am working on a frontend Python precompiler for it.

I heard about Twisted Matrix a while back, but I didn't think much of it. Guess I'll think it out now.